Theodore L. Thomas
Berkley Publishing Group, 1965
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One night, beneath the streets of the city, four ingredients found their way into the same collector box in the underground sewer system, combined in a warm , seething liquid and gave birth to a hideous, destructive force...
Life is accidentally created in the catch basin of a Chicago drain; this 'clone' grows into a miles-square blob that eats organic material, including people. The city is threatened as the clone adapts to eating parts of buildings.
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